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Tuesday, January 20, 2015
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paraphrase an old TV show title, Perhaps "Father (does) Know Best." Related Articles Sex linkage Estrogen Sex education Turner syndrome Breast implant Human genome Female students who said their dads were "involved" in their lives as teens are more likely to use protection when having sex in college, a positive sign for fathers in an era of increasingly single-parent homes, according to new University of Florida research. For her master's thesis in the UF/IFAS Department of Family, Youth and Community Sciences, Caroline Payne-Purvis analyzed responses from 748 college students in an introductory course at UF. About 60 percent were females, and 40 percent male. Students answered 73 questions, which tried to find out, among other things, aspects of the participants' adolescent years, their parents' level of involvement when the students still lived at home, how often they now engage in sexual behaviors, including intercourse and their contraception use during various sexual behaviors. Payne-Purvis found female students who said their father was "involved" in their lives as teens used condoms more frequently during intercourse. Females who reported higher rates of father involvement reported engaging in sexual intercourse less frequently and with fewer partners. Furthermore, the more involved mothers were doing a female college student's adolescence, the more often the young women used hormonal contraceptives. Payne-Purvis, now an assistant professor in health and kinesiology at the Mississippi University for Women, said it's hard to explain the finding. One possible explanation she proffers in the paper is that the presence of a father figure in females' adolescent lives reduces the desire for male attention outside the home. "The main lesson to take from this study is that in an era of single families, high divorce rates and dual working families, fathers continue to have an impact on their daughters' lives," she said. "Additionally, it indicates that situations and relationships from one's adolescence carry over into early adulthood." In the paper, published in the Journal of Adolescent and Family Health, Payne-Purvis wrote that mothers have historically taught their daughters about sex, while fathers have educated their sons about the birds and the bees. Payne-Purvis' study was part of a larger examination of contraceptive use among college students. She wrote the paper with Professor Rosemary Barnett and Associate Professor Larry Forthun, both in the UF/IFAS' family, youth and community sciences department.
Thursday, January 15, 2015
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Study supports link between injectable hormonal contraceptive and HIV risk Worldwide about 144 million women use hormonal contraception--around 41 million use the injectable forms and 103 million take the oral contraceptive pill. Whether or not use of hormonal contraceptives increases women's risk of HIV acquisition has been hotly debated for more than two decades. But research so far has been inconclusive. Researchers from the University of California at Berkeley in the USA conducted a meta-analysis of all existing data examining the effect of using the most commonly prescribed forms of hormonal contraception (combined oral contraceptives, progestin-only pills, and the injectable contraceptives DMPA and norethisterone enanthate) on HIV risk up to June, 2014. Analysis of 12 observational studies from sub-Saharan Africa involving 39 560 women suggest that DMPA use increases a woman's chance of becoming infected with HIV by 40% compared with women using other contraceptive methods or no method. Although statistically significant, this represents only a moderate increase in relative risk. This risk appears to be lower among women in the general population (increase 31%) than for women already at high risk of acquiring HIV such as sex workers. However, the limited number of studies on high risk women leaves uncertainty for this important subgroup of women. No increased risk was noted for users of oral contraceptive pills, combined oral contraceptives, or norethisterone enanthate. "The moderate elevation in risk observed in our study is not enough to justify a complete withdrawal of DMPA for women in the general population," cautions Lauren Ralph, lead author and an epidemiologist at the University of California at Berkeley. "Banning DMPA would leave many women without immediate access to alternative, effective contraceptive options. This is likely to lead to more unintended pregnancies, and because childbirth remains life-threatening in many developing countries, could increase overall deaths among women."
Sunday, January 11, 2015
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College Teen Enjoying First Time Sex Long-acting drug effectively prevents HIV-like infection in monkeys "Clinical trial results have demonstrated that the effectiveness of preventive oral medications can range with results as high as 75 percent effective to as low as ineffective, and a lot of that variability appears to hinge on the patient's ability to take the pills as prescribed," says study researcher Martin Markowitz, a professor at Rockefeller University and ADARC. "Long acting cabotegravir has the potential to create an option that could improve adherence by making it possible to receive the drug by injection once every three months." Developed by ViiV Healthcare and GlaxoSmithKline, and previously known as GSK744 LA, cabotegravir is an antiretroviral drug. Antiretrovirals interfere with HIV's ability to replicate itself using a host cell and they are used to treat an HIV infection or to prevent those at high risk from acquiring it in the first place. Cabotegravir belongs to a group of antiretrovirals that target integrase, an enzyme the virus uses to integrate itself into the cell's genome. This compound is a relative of an already FDA-approved integrase inhibitor, dolutegravir, but with chemical properties that allow it to be formulated into a long-acting suspension for injection. A previous study by the ADARC and Rockefeller team in collaboration with ViiV Healthcare and GSK found long-acting cabotegravir could protect male rhesus macaque monkeys from exposure to a virus related to HIV. Following up on these results, a phase 2 clinical trial is now underway in a group of 120 men at low risk of infection. Before cabotegravir's effectiveness in high risk individuals can be tested, trials must show that study participants tolerate the drug well and find the quarterly injections, which are a novel approach to HIV prevention, acceptable. Both new animal studies were conducted with women in mind; in 2013 women accounted for 47 percent of new HIV infections worldwide according to the Joint United Nations Programme on HIV and AIDS. Working separately, two teams tested the drug's ability to block vaginal transmission in two species of monkeys with different breeding cycles and susceptibility to infection. First author Chasity Andrews, a postdoctoral fellow at ADARC and Rockefeller, and colleagues at ADARC, the Tulane Regional Primate Center and ViiV/GSK, studied female rhesus macaques treated with progesterone to increase their susceptibility to the virus. They found injections of long acting cabotegravir were 90 percent effective at protecting the monkeys from repeated high-dose exposures to the virus. Meanwhile, the complementary study conducted by researchers at the CDC and ViiV/GSK found female pigtail macaques injected with cabotegravir were completely protected against multiple exposures to the virus. "While we are still a long way off from showing that this drug works for HIV prevention in humans, our hope is that it may one day offer high risk women, as well as men, an additional option for HIV prevention," Markowitz says. "One of the lessons we have learned from contraception is the more options available, the better. We are hoping for the same in HIV prevention -- more options and better results."
Saturday, January 10, 2015
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Risk of HIV infection in studies of African women using hormonal contraceptives While combining data from many studies improves statistical power, the researchers note that the associations between hormonal contraception and risk of becoming infected with HIV were attenuated for studies at lower risk of methodological bias compared to those at higher risk of bias, suggesting that some of the risk found to be associated with hormonal contraception may be due to bias in the original studies. They stress that a randomized controlled trial would provide more definitive evidence of the effects of hormonal contraception on HIV risk. Until such studies are conducted, they conclude that "women with high HIV risk need access to additional safe and effective contraceptive options, and they need to be counseled about the relative risks and benefits of the available family planning methods."
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The man who's had TWO sex changes: Incredible story of Walt, who became Laura, then REVERSED the operation because he believes surgeons in US and Europe are too quick to operate Walt Heyer had sex change to become a woman when he was 42 years old After eight years living as Laura Jensen, he reverted back to being a man He believes the desire to change gender stems from psychological trauma Heyer controversially disputes that Gender Dysphoria is a genetic disorder Now 74, he acts as a counselor to those considering a sex change surgery Psychological vetting of patients before operation is inadequate, he claims Read more: http://www.dailymail.co.uk/news/article-2921528/The-man-s-TWO-sex-changes-Incredible-story-Walt-Laura-REVERSED-operation-believes-surgeons-quick-operate.html#ixzz3QTCryirN Follow us: @MailOnline on Twitter | DailyMail on Facebook
Monday, January 5, 2015
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The Orgasmic Mind: The Neurological Roots of Sexual Pleasure She did not often have such strong emotions. But she suddenly felt powerless against her passion and the desire to throw herself into the arms of the cousin whom she saw at a family funeral. “It can only be because of that patch,” said Marianne, a participant in a multinational trial of a testosterone patch designed to treat hypoactive sexual desire disorder, in which a woman is devoid of libido. Testosterone, a hormone ordinarily produced by the ovaries, is linked to female sexual function, and the women in this 2005 study had undergone operations to remove their ovaries. After 12 weeks of the trial, Marianne had felt her sexual desire return. Touching herself unleashed erotic sensations and vivid sexual fantasies. Eventually she could make love to her husband again and experienced an orgasm for the first time in almost three years. But that improvement was not because of testosterone, it turned out. Marianne was among the half of the women who had received a placebo patch—with no testosterone in it at all.
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